Biomimetic Catalytic Remote Desaturation of Aliphatic Alcohols
Herein we present photoinduced cobaloxime-catalyzed selective remote desaturation of aliphatic alcohols. This transformation, which proceeds efficiently at room temperature, facilitates the synthesis of valuable cyclic and acyclic allylic and homoallylic alcohols from readily available saturated aliphatic alcohols. Remarkably, this method obviates the need for external oxidants, noble metal catalysts, and phosphine ligands.
Authors
- Kaiming Zuo (ORCID: https://orcid.org/0000-0003-4037-2450)
- Jing Zhu (ORCID: https://orcid.org/0000-0001-5555-8560)
- Phong Dam (ORCID: https://orcid.org/0000-0003-3438-181X)
- Luis Miguel Azofra (ORCID: https://orcid.org/0000-0003-4974-1670)
- Osama El‐Sepelgy (ORCID: https://orcid.org/0000-0003-3131-4988)
- Faral Akhtar
Institutions
- Universidad de Las Palmas de Gran Canaria (ES)
- Leibniz Institute for Catalysis (DE)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1021/acs.orglett.4c03623
- Citations
- 8
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 1.48
Funders
- European Commission
- Deutsche Forschungsgemeinschaft
- China Scholarship Council
- Agencia Estatal de Investigación