Brain-type natriuretic peptide is a useful biomarker of cardiovascular disease and predictor of cardiac-related mortality in chimpanzees (Pan troglodytes)
Cardiovascular disease is a leading cause of morbidity and mortality in great apes, and sudden cardiac death with few to no preceding clinical signs is common in chimpanzees. A biomarker for occult heart disease could help identify individuals requiring monitoring or intervention. Brain-type natriuretic peptide is a useful biomarker for heart disease in chimpanzees, which has important clinical relevance for facilities that house captive chimpanzees.
Authors
- Elizabeth R. Magden (ORCID: https://orcid.org/0000-0002-1312-2694)
- Angela M. Achorn (ORCID: https://orcid.org/0000-0002-3425-2551)
- William Donald Hopkins (ORCID: https://orcid.org/0000-0003-3480-1853)
- Carolyn Jones
- Martha E. Hensel (ORCID: https://orcid.org/0000-0001-8520-0279)
- Carolyn L. Hodo (ORCID: https://orcid.org/0000-0003-4113-7081)
- Stephanie J. Buchl
- Elizabeth A. Piatt
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- American Journal of Veterinary Research
- Published
- 2024-12-23
- DOI
- https://doi.org/10.2460/ajvr.24.09.0287
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health