Bis(oxazoline) Iron Complexes Enable Tuning of Lewis Acidity for Catalytic Carbonyl–Olefin Metathesis
Carbonyl–olefin metathesis reactions are powerful transformations for carbon–carbon bond formation. Despite recent progress, limitations exist that hamper the synthetic generality of the reported approaches. Catalytic systems that will enable tuning of their Lewis acidity and consequently the selective activation of specific substrate classes are expected to greatly enhance the current scope. We herein report the development of cationic iron-bis(oxazoline) complexes as powerful catalysts that enable the alteration of Lewis acidity to efficiently convert substrate types that were previously found to be incompatible with existing catalytic systems in carbonyl–olefin ring-closing metathesis.
Authors
- Ashlee J. Davis (ORCID: https://orcid.org/0000-0003-3347-7537)
- Daniel C. Steigerwald
- Mu‐Hyun Baik (ORCID: https://orcid.org/0000-0002-8832-8187)
- Rebecca B. Watson (ORCID: https://orcid.org/0000-0003-1116-7052)
- Corinna S. Schindler (ORCID: https://orcid.org/0000-0003-4968-8013)
- Mina Son (ORCID: https://orcid.org/0000-0001-5689-1648)
- Jessica L. Gomez-Lopez (ORCID: https://orcid.org/0000-0002-5299-9616)
- Timothy J. McClure
Institutions
- University of British Columbia (CA)
- Korea Advanced Institute of Science and Technology (KR)
- University of Michigan (US)
- Institute for Basic Science (KR)
Publication Details
- Journal
- ACS Catalysis
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1021/acscatal.3c04684
- Citations
- 4
- Primary Topic
- Synthetic Organic Chemistry Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.00
Funders
- National Science Foundation
- David and Lucile Packard Foundation
- Alfred P. Sloan Foundation
- Camille and Henry Dreyfus Foundation
- Consejo Nacional de Ciencia y Tecnología
- Institute for Basic Science
- National Institute of General Medical Sciences