Evaluation of novel recombinant antigen-based (NIE/SsIR) immunochromatographic rapid tests for Strongyloides stercoralis: an accuracy study
The IgG-RDT demonstrated higher sensitivity and could hence be preferred for individual diagnosis, whereas the excellent specificity of the IgG4-RDT could be preferred for prevalence surveys in endemic areas. The results of both RDTs were easy to interpret based on excellent agreement between readers. Large prospective studies should follow to confirm these findings and to validate the use of either RDT for specific purposes/contexts.
Authors
- Cristina Mazzi
- Francesca Tamarozzi (ORCID: https://orcid.org/0000-0003-0478-3914)
- Dora Buonfrate (ORCID: https://orcid.org/0000-0003-0108-6822)
- Monica Degani
- Stefano Tais
- Eleonora Rizzi (ORCID: https://orcid.org/0000-0001-9615-2452)
- Salvatore Scarso (ORCID: https://orcid.org/0000-0003-2956-8997)
Institutions
- Ospedale Sacro Cuore Don Calabria (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s13071-024-06569-y
- Citations
- 3
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Ministero della Salute