Development and evaluation of deuterated [18F]JHU94620 isotopologues for the non-invasive assessment of the cannabinoid type 2 receptor in brain
These results support further investigations of [<sup>18</sup>F]JHU94620-d<sub>8</sub> in pathological models and tissues with a CB2R overexpression as a prerequisite for clinical translation.
Authors
- Daniel Gündel (ORCID: https://orcid.org/0000-0001-9743-2325)
- Klaus Kopka (ORCID: https://orcid.org/0000-0003-4846-1271)
- Winnie Deuther‐Conrad (ORCID: https://orcid.org/0000-0003-3168-3062)
- Magali Toussaint (ORCID: https://orcid.org/0000-0002-1136-3857)
- Friedrich‐Alexander Ludwig (ORCID: https://orcid.org/0000-0002-4358-5171)
- Rodrigo Teodoro (ORCID: https://orcid.org/0000-0002-1425-0567)
- Guy Bormans (ORCID: https://orcid.org/0000-0002-0335-7190)
- Peter Brust (ORCID: https://orcid.org/0000-0001-5555-7058)
- Rareş‐Petru Moldovan (ORCID: https://orcid.org/0000-0003-3119-7945)
- Anne Heerklotz
- Mudasir Maqbool (ORCID: https://orcid.org/0000-0002-8213-6715)
Institutions
- National Institutes of Health (US)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- Institute for Integrative and Experimental Genomics (DE)
- National Institute of Mental Health (US)
- ABT Molecular Imaging (United States) (US)
- Technische Universität Dresden (DE)
- University of Lübeck (DE)
- KU Leuven (BE)
Publication Details
- Journal
- EJNMMI Radiopharmacy and Chemistry
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s41181-024-00319-2
- Citations
- 3
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.34
Funders
- Deutsche Forschungsgemeinschaft
- Universität Leipzig
- Helmholtz-Zentrum Dresden-Rossendorf
- Ústav analytické chemie, Akademie Věd České Republiky