High Interleukin (IL)-6 is Associated with Lower Lung Function and Increased Likelihood of Metabolic Dysfunction in Asthma
This study underscores the significant association between IL-6, asthma, obesity, and metabolic dysfunction. Elevated IL-6 correlates with asthma severity, particularly in individuals with obesity. Future research should explore anti-IL-6 therapies for specific phenotypes, such as obesity-related asthma. These findings advance our understanding of asthma and the role of IL-6 in its pathogenesis.
Authors
- Njira Lucia Lugogo (ORCID: https://orcid.org/0000-0002-0235-7105)
- Amir Behzad Bagheri (ORCID: https://orcid.org/0000-0003-1015-329X)
- D ADAIR
- Shokoufeh Khalatbari (ORCID: https://orcid.org/0000-0001-6674-0763)
- Toby C. Lewis (ORCID: https://orcid.org/0009-0001-2524-1025)
- Arjun Mohan (ORCID: https://orcid.org/0000-0002-6190-7592)
- Matheos Yosef
Institutions
- Augusta University (US)
- University of Michigan (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Pulmonary Therapy
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1007/s41030-024-00281-z
- Citations
- 5
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.63