The Alzheimer's Association clinical practice guideline for the diagnostic evaluation, testing, counseling, and disclosure of suspected Alzheimer's disease and related disorders (DETeCD‐ADRD): Validated clinical assessment instruments

US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's Disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence-based guideline was developed to empower all-including primary care-clinicians to implement a structured approach for evaluating a patient with symptoms that may represent clinical AD/ADRD. As part of the modified Delphi approach and guideline development process (7374 publications were reviewed; 133 met inclusion criteria) an expert workgroup developed recommendations as steps in a patient-centered evaluation process. The workgroup provided a summary of validated instruments to measure symptoms in daily life (including cognition, mood and behavior, and daily function) and to test for signs of cognitive impairment in the office. This article distills this information to provide a resource to support clinicians in the implementation of this approach in clinical practice. The companion articles provide context for primary care and specialty clinicians with regard to how to fit these instruments into the workflow and actions to take when integration of performance on these instruments with clinical profile and clinician judgment support potential cognitive impairment.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-23
DOI
https://doi.org/10.1002/alz.14335
Citations
16
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
6.17

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article

The Alzheimer's Association clinical practice guideline for the diagnostic evaluation, testing, counseling, and disclosure of suspected Alzheimer's disease and related disorders (DETeCD‐ADRD): Validated clinical assessment instruments

Alireza Atri, Jason Karlawish, Susan Scanland, Chiadi U. Onyike et al.
16 citations
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
6.17
article

The Alzheimer's Association clinical practice guideline for the diagnostic evaluation, testing, counseling, and disclosure of suspected Alzheimer's disease and related disorders (DETeCD‐ADRD): Validated clinical assessment instruments

Alireza Atri, Jason Karlawish, Susan Scanland, Chiadi U. Onyike, Pei‐Jung Lin, Mary S. Norman, Bradford Clark Dickerson, Carolyn Clevenger, Marı́a C. Carrillo, Mary Sano, David S. Knopman
article en
16 citations

Abstract

US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's Disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence-based guideline was developed to empower all-including primary care-clinicians to implement a structured approach for evaluating a patient with symptoms that may represent clinical AD/ADRD. As part of the modified Delphi approach and guideline development process (7374 publications were reviewed; 133 met inclusion criteria) an expert workgroup developed recommendations as steps in a patient-centered evaluation process. The workgroup provided a summary of validated instruments to measure symptoms in daily life (including cognition, mood and behavior, and daily function) and to test for signs of cognitive impairment in the office. This article distills this information to provide a resource to support clinicians in the implementation of this approach in clinical practice. The companion articles provide context for primary care and specialty clinicians with regard to how to fit these instruments into the workflow and actions to take when integration of performance on these instruments with clinical profile and clinician judgment support potential cognitive impairment.

Alzheimer s & DementiaVol. 21(1)
Alzheimer's Association (US), Cedars-Sinai Medical Center (US), Brigham and Women's Hospital (US), Tufts Medical Center (US), Mayo Clinic (US), Harvard University (US), Johns Hopkins University (US), Emory University (US), Johns Hopkins Medicine (US), Massachusetts General Hospital (US), James J. Peters VA Medical Center (US), Banner Sun Health Research Institute (US), Banner Alzheimer’s Institute, University of Pennsylvania (US), Icahn School of Medicine at Mount Sinai (US)
Alzheimer's Association
Openalex Percentile: Top 2%
Dementia and Cognitive Impairment Research
6.17
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