Attenuated sex-related DNA methylation differences in cancer highlight the magnitude bias mediating existing disparities
These findings advance our understanding of how sex, DNAm, and gene expression interact in cancer, offering insights into the development of sex-specific biomarkers and precision medicine.
Authors
- Shangzi Wang (ORCID: https://orcid.org/0000-0002-8936-6572)
- Danke Wang
- Xingdong Chen (ORCID: https://orcid.org/0000-0003-3763-160X)
- Chen Suo (ORCID: https://orcid.org/0000-0002-5274-4584)
- Miao Li (ORCID: https://orcid.org/0009-0004-8775-686X)
- Yu Chen (ORCID: https://orcid.org/0000-0002-1519-4894)
- Jiaqi Zhou (ORCID: https://orcid.org/0009-0005-4139-9606)
Institutions
- Broad Institute (US)
- Harvard University (US)
- Kunming Institute of Zoology (CN)
- Chinese Academy of Sciences (CN)
- Fudan University (CN)
- Massachusetts General Hospital (US)
- Yiwu Science and Technology Research Institute (CN)
- Huashan Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s13293-024-00682-4
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China