Persistent urticarial eruption preceding systemic features of adult‐onset Still's disease: A case report

Adult-onset Still's disease (AOSD) is a rare autoinflammatory systemic disorder classically characterised by inflammatory polyarthritis, daily fevers and a transient asymptomatic salmon-pink maculopapular rash that typically arises with the onset of fevers. We report a case of AOSD presenting with a severely pruritic urticarial eruption starting 6 weeks prior to the onset of fever and arthritis and complicated by macrophage activation syndrome. This case highlights the importance of early recognition of diverse cutaneous manifestations of AOSD to facilitate timely diagnosis and treatment to improve disease outcomes.

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Publication Details

Journal
Australasian Journal of Dermatology
Published
2024-12-23
DOI
https://doi.org/10.1111/ajd.14397
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
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article

Persistent urticarial eruption preceding systemic features of adult‐onset Still's disease: A case report

Shereen Oon, Amreeta Kaur, Emma Veysey, Mathuja Bavanendrakumar
Australasian Journal of Dermatology
Autoimmune and Inflammatory Disorders Research
article

Persistent urticarial eruption preceding systemic features of adult‐onset Still's disease: A case report

Shereen Oon, Amreeta Kaur, Emma Veysey, Mathuja Bavanendrakumar
article en

Abstract

Adult-onset Still's disease (AOSD) is a rare autoinflammatory systemic disorder classically characterised by inflammatory polyarthritis, daily fevers and a transient asymptomatic salmon-pink maculopapular rash that typically arises with the onset of fevers. We report a case of AOSD presenting with a severely pruritic urticarial eruption starting 6 weeks prior to the onset of fever and arthritis and complicated by macrophage activation syndrome. This case highlights the importance of early recognition of diverse cutaneous manifestations of AOSD to facilitate timely diagnosis and treatment to improve disease outcomes.

Australasian Journal of DermatologyVol. 66(2)
Royal Women's Hospital (AU), The University of Melbourne (AU), St Vincent's Hospital Melbourne (AU), Skin Health Institute (AU)
Good health and well-being
Openalex Percentile: Top 56%
Autoimmune and Inflammatory Disorders Research
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Persistent urticarial eruption preceding systemic features of adult‐onset Still's disease: A case report — Shereen Oon, Amreeta Kaur, et al. · Australasian Journal of Dermatology (2024) | TGRS Research Map | TGRS