Fumarate Hydratase–Deficient Renal Cell Carcinoma With Paraganglioma Detected on 18F-FDG PET/CT

We report FDG PET/CT findings of fumarate hydratase-deficient renal cell carcinoma coincidence with para-aortic paraganglioma in a 27-year-old man. He presented with painless gross hematuria for 3 days. CT identified an enhancing lesion in the left kidney, suggestive of a tumor. 18 F-FDG PET/CT imaging showed the mass with high FDG uptake. An adjacent FDG-avid nodule was also noted. Postoperative pathology supported a diagnosis of fumarate hydratase-deficient renal cell carcinoma of the left kidney mass, and the adjacent nodule was paraganglioma.

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Journal
Clinical Nuclear Medicine
Published
2024-12-23
DOI
https://doi.org/10.1097/rlu.0000000000005645
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Fumarate Hydratase–Deficient Renal Cell Carcinoma With Paraganglioma Detected on 18F-FDG PET/CT

Yan Deng, Limeng He, Ji Wu, Wei Zhang
Clinical Nuclear Medicine
Renal cell carcinoma treatment
article

Fumarate Hydratase–Deficient Renal Cell Carcinoma With Paraganglioma Detected on 18F-FDG PET/CT

Yan Deng, Limeng He, Ji Wu, Wei Zhang
article en

Abstract

We report FDG PET/CT findings of fumarate hydratase-deficient renal cell carcinoma coincidence with para-aortic paraganglioma in a 27-year-old man. He presented with painless gross hematuria for 3 days. CT identified an enhancing lesion in the left kidney, suggestive of a tumor. 18 F-FDG PET/CT imaging showed the mass with high FDG uptake. An adjacent FDG-avid nodule was also noted. Postoperative pathology supported a diagnosis of fumarate hydratase-deficient renal cell carcinoma of the left kidney mass, and the adjacent nodule was paraganglioma.

Clinical Nuclear MedicineVol. 50(3)
University of Electronic Science and Technology of China (CN), Pediatrics and Genetics (US), Chengdu University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 57%
Renal cell carcinoma treatment
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