Case Report: Catastrophic antiphospholipid syndrome in a pediatric patient after percutaneous treatment of aortic re-coarctation
A female patient in middle childhood was diagnosed with coarctation of the aorta at one month of age and underwent a successful cortectomy. At 11 years old, she developed re-coarctation, which was managed through interventional cardiology. Shortly after the procedure, she experienced a sudden and severe clinical decline, presenting with hypoperfusion of the lower extremities, gastrointestinal bleeding, acute kidney injury, and pancreatitis. Multiple thrombotic events were identified, prompting an extensive evaluation for thrombophilia<b>.</b> The patient tested positive for antiphospholipid antibodies and was diagnosed with catastrophic antiphospholipid antibody syndrome (CAPS). An aggressive treatment was initiated, yielding a favorable response following discharge; she made a full recovery and continues to be monitored regularly in cardiology and rheumatology clinics.
Authors
- Javier Merayo Chalico
- Luis Alberto Aparicio Vera (ORCID: https://orcid.org/0000-0002-3034-0415)
- Iris Paola García Herrera
- Carlos Canales Robredo
- Magdalena Aboytes Zavala
- Orfanel Sebastian Pineda Arzate
- José Luis Colín Ortíz
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-12-20
- DOI
- https://doi.org/10.3389/fped.2024.1410400
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00