Ketamine Reduces Avoidance Responses During Re-Exposition to Aversive Stimulus: Comparison Between (S)-Isomer and Racemic Mixture
These findings reinforce the therapeutic potential of ketamine for the treatment of stress-related disorders, with (<i>R</i>,<i>S</i>)-ketamine being more effective in simultaneously inducing antidepressant and anxiolytic responses and reducing avoidance responses in stressed mice.
Authors
- Clarissa de Almeida Moura (ORCID: https://orcid.org/0000-0001-6186-2526)
- Ana Beatriz Aroeira Soares (ORCID: https://orcid.org/0009-0001-8869-7943)
- Hindiael Belchior (ORCID: https://orcid.org/0000-0002-6898-3985)
- Elaine C. Gavioli (ORCID: https://orcid.org/0000-0001-8967-1369)
- Edilson Dantas da Silva (ORCID: https://orcid.org/0000-0001-5505-8056)
- Carina Ioná de Oliveira Torres (ORCID: https://orcid.org/0000-0003-4764-9029)
- Anne N. de Sousa-Silva (ORCID: https://orcid.org/0000-0002-4645-8389)
Institutions
- Universidade Federal do Rio Grande do Norte (BR)
Publication Details
- Journal
- Brain Sciences
- Published
- 2024-12-22
- DOI
- https://doi.org/10.3390/brainsci14121291
- Citations
- 1
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Apoio à Pesquisa do Rio Grande do Norte