Sex- and Substance-Specific Associations of Circadian-Related Genes with Addiction in the UK Biobank Cohort Implicate Neuroplasticity Pathways

Our findings underscore the complexity of genetic pathways associated with addiction, involving core clock genes and circadian-regulated pathways, and reveal novel circadian-related gene associations that will aid the development of targeted, sex-specific therapeutic interventions for substance abuse.

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Publication Details

Journal
Brain Sciences
Published
2024-12-20
DOI
https://doi.org/10.3390/brainsci14121282
Citations
2
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.55

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article

Sex- and Substance-Specific Associations of Circadian-Related Genes with Addiction in the UK Biobank Cohort Implicate Neuroplasticity Pathways

Ziad Attia, Krista K. Ingram, Ahmet Ay, Mete Minbay et al.
2 citations
Brain Sciences
Circadian rhythm and melatonin
0.55
article

Sex- and Substance-Specific Associations of Circadian-Related Genes with Addiction in the UK Biobank Cohort Implicate Neuroplasticity Pathways

Ziad Attia, Krista K. Ingram, Ahmet Ay, Mete Minbay, Ayub Khan
article en
2 citations

Abstract

Our findings underscore the complexity of genetic pathways associated with addiction, involving core clock genes and circadian-regulated pathways, and reveal novel circadian-related gene associations that will aid the development of targeted, sex-specific therapeutic interventions for substance abuse.

Brain SciencesVol. 14(12)
Colgate University (US)
Colgate University
Good health and well-being
Openalex Percentile: Top 34%
Circadian rhythm and melatonin
0.55
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