Comparative study of transcriptomic alterations in sepsis-induced acute liver injury: Deciphering the role of alternative splicing in mouse models
This study offers a comprehensive insight into the role of AS in sepsis-induced ALI, laying the groundwork for future therapeutic interventions. By demonstrating the functional relevance of specific splicing events, such as those involving Nop58, this work underscores the potential of targeting splicing mechanisms as innovative strategies to mitigate sepsis-induced liver injuries.
Authors
- Songtao Jia (ORCID: https://orcid.org/0000-0002-7927-0227)
- Muzaipaier Tuerxun
- Yi Fang (ORCID: https://orcid.org/0000-0002-3001-7028)
- Yugang Zhuang (ORCID: https://orcid.org/0000-0002-6304-6765)
- Huaguo Chen
- Nana Tong
- Mingming Sun (ORCID: https://orcid.org/0000-0002-3117-7066)
- Peng Hu (ORCID: https://orcid.org/0000-0002-2144-9806)
- Dan Liu (ORCID: https://orcid.org/0000-0003-4341-0010)
- Ke Nie
- Yuanzhuo Chen
- Aimaitijiang Kadier
- Aisikaer Aisha
- Jinxia Jiang
Institutions
- Tongji University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Shanghai Tenth People's Hospital (CN)
- Kashi University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1016/j.intimp.2024.113878
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Natural Science Foundation of Xinjiang Province
- National Natural Science Foundation of China
- Shanghai Shenkang Hospital Development Center