Visible-light-induced aerobic oxidative cyclization of nitroarenes with triethylamine using an organophotocatalyst
Isoxazolidines are structurally important scaffolds in many natural products and bioactive compounds. Herein, we report a novel synthetic method for isoxazolidine derivatives through visible-light-induced photoredox cascade cyclization of nitroarenes with triethylamine under aerobic conditions. The resultant 5-hydroxyl isoxazolidine compounds were generally obtained in moderate yields with a broad range of compatible functionalities.
Authors
- Huawen Huang (ORCID: https://orcid.org/0000-0001-7079-1299)
- Guo‐Jun Deng (ORCID: https://orcid.org/0000-0003-2759-0314)
- Yi Zhou (ORCID: https://orcid.org/0000-0003-4809-0749)
- Yutong He (ORCID: https://orcid.org/0000-0002-5588-622X)
Institutions
- Xiangtan University (CN)
- Henan Normal University (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1039/d4ob01714e
- Citations
- 2
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- Henan Normal University
- National Natural Science Foundation of China