Optimal intervention timing for craniocerebral radiotherapy in EGFR mutant lung adenocarcinoma patients with brain metastases
For patients with craniocerebral metastases of EGFR-mutant lung adenocarcinoma, combination of EGFR-TKIs and craniocerebral RT confers enhanced survival benefits. In patients with lower Lung-molGPA scores, delayed administration of craniocerebral RT is recommended to improve both iPFS and OS.
Authors
- Jing Fan (ORCID: https://orcid.org/0000-0002-2663-1471)
- Guangchuan Deng (ORCID: https://orcid.org/0000-0003-2614-8161)
- Chunlin Zhao (ORCID: https://orcid.org/0000-0003-1333-1864)
- Hui Jiao
- Zhenxiang Li
- Qunxing Zhang
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Shandong Tumor Hospital (CN)
- Shandong Provincial Hospital (CN)
- Jimo District Qingdao Hospital of Traditional Chinese Medicine (CN)
- Shandong First Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s12885-024-13363-7
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- National Natural Science Foundation of China