Analytical Study of Yoganjana Ointment: An Ayurvedic Formulation

Anjana is an Ayurvedic medicinal formulation that is used in “Sampakvadosha” condition.1 Anjana also known as collyrium is a topical application of drug in the form of smooth paste into the conjunctival fornices with an applicator. Although Anjanas are meant for eye diseases yet it has wide application in systemic diseases too. Anjana is used when the acute inflammatory features subside and the clinical feature of each dosha become manifested and localized in the eye. Anjana preparation are compound drugs prepared out of metal, minerals, herbs and animal materials. Generally Arsenic, Antimony, Lead and Tin compounds are frequently prescribed. Dosage and duration are aptly prescribed to avoid noncompliance. Disposal of the drug is very minimal so the tissue contact time is more; absorption is maximum thus bioavailability is naturally more. Probably, it acts as subconjunctival injection, permeability is also possible through the sclera and enters into the systemic circulation and may act on posterior segmental disorders of the eye. The metals in Anjana preparation having larger molecular weight do not cross the blood aqueous barrier when administered systematically. The treatment plan of Praklinna Vartma mentioned in Sushruta Samhita includes Yoganjana along with other ocular therapeutic procedures. Yoganjana is an Ayurvedic formulation mentioned in Sushruta Samhita used to treat Vartmagata disease namely Praklinna Vartma. Keeping all the points, this study has been undertaken with the aim to modify Yoganjana in ointment form. The Anjana was prepared through “Ghana Satva Kalpana”.