Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients

Our study indicated that <i>GABRA1</i> rs10068980 and <i>SLC16A1</i> rs7169 might serve as potential biomarkers for predicting the 12-month VPA treatment outcomes in pediatric patients with epilepsy.

Authors

Institutions

Publication Details

Journal
Personalized Medicine
Published
2024-12-22
DOI
https://doi.org/10.1080/17410541.2024.2441655
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients

Heng Liang, Ruyu Tao, Chen Qian, Haijun Wu et al.
Personalized Medicine
Pharmacological Effects and Toxicity Studies
article

Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients

Heng Liang, Ruyu Tao, Chen Qian, Haijun Wu, Yanling Pan, Zhijun Zhong, Changsong Wu, Jianghuan Zheng
article en

Abstract

Our study indicated that <i>GABRA1</i> rs10068980 and <i>SLC16A1</i> rs7169 might serve as potential biomarkers for predicting the 12-month VPA treatment outcomes in pediatric patients with epilepsy.

Personalized MedicineVol. 22(1)
Guiyang Medical University (CN), Sun Yat-sen University (CN), Guizhou University (CN), Affiliated Hospital of Guizhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 63%
Pharmacological Effects and Toxicity Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients — Heng Liang, Ruyu Tao, et al. · Personalized Medicine (2024) | TGRS Research Map | TGRS