The role of APOE gene polymorphisms in lung adenocarcinoma susceptibility and lipid profile
Individuals carrying the ϵ2 allele have an increased susceptibility to developing LUAD, accompanied by disrupted lipid metabolism. Additionally, the APOE ϵ2/ϵ2 and ϵ2/ϵ3 genotypes are associated with an increased risk of developing advanced and poorly differentiated LUAD.
Authors
- Dunqiang Ren (ORCID: https://orcid.org/0000-0002-9601-7899)
- Huanhuan Bi (ORCID: https://orcid.org/0000-0002-9899-8774)
- Hongmei Wang (ORCID: https://orcid.org/0000-0003-1603-4785)
- Chunling Zhang (ORCID: https://orcid.org/0000-0003-2752-1028)
- Ye Wang (ORCID: https://orcid.org/0000-0002-5383-2690)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1522761
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Wu Jieping Medical Foundation