Can there be calm during a cytokine storm? Immune checkpoint pathways affecting the severity of COVID-19 disease
These findings shed light on the intricate immune response regulation in COVID-19, emphasizing the importance of immune checkpoint pathways and activation signatures in disease severity. A novel aspect of this study is that it includes only COVID-19 patients experiencing cytokine storms, allowing for a focused analysis of immune dysregulation during this critical phase of the disease.
Authors
- Timoteus Feik (ORCID: https://orcid.org/0000-0002-7776-5226)
- László Szereday (ORCID: https://orcid.org/0000-0002-1208-2969)
- Mátyás Meggyes (ORCID: https://orcid.org/0000-0002-9913-2024)
- Ágnes Péterfalvi
- Beáta Polgár (ORCID: https://orcid.org/0000-0002-8687-7430)
- Dávid Sipos (ORCID: https://orcid.org/0000-0001-9615-1740)
- Ágnes Kemény (ORCID: https://orcid.org/0000-0002-4523-3938)
- Dávid U. Nagy (ORCID: https://orcid.org/0000-0001-7742-4459)
- Ildikó Y. Tóth (ORCID: https://orcid.org/0000-0002-4937-0526)
Institutions
- Szent János Kórház (HU)
- Martin Luther University Halle-Wittenberg (DE)
- University of Pecs (HU)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fmicb.2024.1508423
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.39