Adult neurogenesis in the ventral hippocampus decreased among animal models of neurodevelopmental disorders
These findings suggest that impaired adult neurogenesis in the ventral hippocampus is a common hallmark across ASD mouse models and may underlie social behavior deficits. This study provides insight into region-specific neurogenic alterations linked to ASD pathophysiology and highlights potential targets for therapeutic interventions.
Authors
- Takuma Mori (ORCID: https://orcid.org/0000-0002-4195-2804)
- Qi Guo (ORCID: https://orcid.org/0000-0002-9558-9633)
- Yoshinori Shirai (ORCID: https://orcid.org/0000-0002-3263-4986)
- Emi Kouyama-Suzuki
- Katsuhiko Tabuchi (ORCID: https://orcid.org/0000-0002-1673-4637)
- Yoshikuni Mizuno (ORCID: https://orcid.org/0000-0002-1588-5134)
- Li‐hao Sun (ORCID: https://orcid.org/0000-0001-9319-9386)
- Nobuhiko Ohashi
- Weichen Zang
Institutions
- Shinshu University (JP)
Publication Details
- Journal
- Frontiers in Neural Circuits
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fncir.2024.1504191
- Citations
- 4
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 1.37
Funders
- SENSHIN Medical Research Foundation
- Japan Society for the Promotion of Science