Characterization of a novel AEL allele harboring a c.28 + 5G>A mutation on the ABO*A2.01 background: a study utilizing PacBio third-generation sequencing and functional assays
A novel <i>AEL</i> allele was identified in a Chinese male blood donor on the <i>ABO*A2.01</i> background, characterized by the c.28 + 5G>A variant. This study provides insights into the molecular basis of blood group antigen variation.
Authors
- Lingzi Pan
- Lin‐Nan Shao (ORCID: https://orcid.org/0000-0002-9025-4957)
- Xiaohua Liang (ORCID: https://orcid.org/0000-0003-3867-9779)
- Shihang Zhou (ORCID: https://orcid.org/0000-0001-9295-7747)
- Lu Zhou (ORCID: https://orcid.org/0000-0002-2688-7135)
- Ying Duan (ORCID: https://orcid.org/0000-0001-7194-7072)
- Nan Xiao (ORCID: https://orcid.org/0000-0001-8150-7118)
- Wenqian Song (ORCID: https://orcid.org/0009-0008-1280-0204)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1396426
- Citations
- 4
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 1.82