RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells

RBM15-mediated m6A methylation enhances KLF1 expression and suppresses TRIM13 via YTHDF1/YTHDF2, thereby promoting ANXA8 and facilitating NSCLC progression. These findings provide novel insights and potential therapeutic targets for NSCLC treatment.

Authors

Xiaoqi Ai
Man Wang (ORCID: https://orcid.org/0000-0003-0859-3501)
Ya‐Zhen Qin (ORCID: https://orcid.org/0000-0002-1548-0946)
Xiuhua Liu

Institutions

Jilin University (CN)
First Hospital of Jilin University (CN)

Publication Details

Journal: Molecular Medicine
Published: 2024-12-23
DOI: https://doi.org/10.1186/s10020-024-01018-z
Citations: 6
Primary Topic: RNA modifications and cancer
Type: article
Field-Weighted Citation Impact: 1.40

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article

RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells

Xiaoqi Ai, Man Wang, Ya‐Zhen Qin, Xiuhua Liu

Dec 23, 2024

6 citations

Molecular Medicine

RNA modifications and cancer

1.40

article

RBM15-dependent m6A modification mediates progression of non-small cell lung cancer cells

Xiaoqi Ai, Man Wang, Ya‐Zhen Qin, Xiuhua Liu

December 23, 2024article en

6 citations

Abstract

Molecular MedicineVol. 30(1)

Jilin University (CN), First Hospital of Jilin University (CN)

Good health and well-being

Openalex Percentile: Top 18%

RNA modifications and cancer

1.40

DOI Open Access PDF OpenAlex

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