Machine learning-based identification of histone deacetylase-associated prognostic factors and prognostic modeling for low-grade glioma

We developed an HDAC-related four-gene prognostic model that correlates with survival, immune landscape, and therapeutic response in LGG patients. This model may guide personalized treatment strategies and improve prognostic accuracy, warranting further validation in clinical settings.

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Publication Details

Journal
Discover Oncology
Published
2024-12-23
DOI
https://doi.org/10.1007/s12672-024-01713-7
Citations
2
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.88
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article

Machine learning-based identification of histone deacetylase-associated prognostic factors and prognostic modeling for low-grade glioma

K.-Y. Wen, Wei Wang, Weijie Zhu, Ziyi Luo
2 citations
Discover Oncology
Glioma Diagnosis and Treatment
0.88
article

Machine learning-based identification of histone deacetylase-associated prognostic factors and prognostic modeling for low-grade glioma

K.-Y. Wen, Wei Wang, Weijie Zhu, Ziyi Luo
article en
2 citations

Abstract

We developed an HDAC-related four-gene prognostic model that correlates with survival, immune landscape, and therapeutic response in LGG patients. This model may guide personalized treatment strategies and improve prognostic accuracy, warranting further validation in clinical settings.

Discover OncologyVol. 15(1)
Longgang Central Hospital (CN), Nanfang Hospital (CN), Southern Medical University (CN)
Quality Education
Openalex Percentile: Top 22%
Glioma Diagnosis and Treatment
0.88
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