Lymphopenia is an adverse prognostic factor in rectal adenocarcinoma patients receiving long-course chemoradiotherapy
Although further investigation is demanded, given the limited number of patients analyzed in the study, lymphopenia emerges as a significant adverse event that rectal adenocarcinoma patients face during treatment with neoadjuvant CRT, with subsequent implications on tumor response and prognosis. Protection of the immune system during CRT emerges as an important target for clinical research.
Authors
- V. Kouloulias
- Ioannis M. Koukourakis (ORCID: https://orcid.org/0000-0003-3143-8585)
- Dina Tiniakos (ORCID: https://orcid.org/0000-0003-4657-7780)
- Ioannis Georgakopoulos (ORCID: https://orcid.org/0000-0002-6354-9805)
- Anna G. Zygogianni (ORCID: https://orcid.org/0000-0001-9698-6852)
- Dimitra Desse (ORCID: https://orcid.org/0000-0002-9074-2395)
Institutions
- National and Kapodistrian University of Athens (GR)
- Newcastle University (GB)
Publication Details
- Journal
- Radiation Oncology Journal
- Published
- 2024-12-23
- DOI
- https://doi.org/10.3857/roj.2024.00052
- Citations
- 2
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57