Integrative metabolomic-proteomic analysis uncovers a new therapeutic approach in targeting rheumatoid arthritis
GUDCA was found to possess antioxidative, antiproliferative properties and an effective anti-inflammatory property at a low dosage. It may be considered as a potential therapeutic option for reducing the inflammatory parameters associated with RA.
Authors
- Mohd Saquib
- Prachi Agnihotri
- Uma Kumar (ORCID: https://orcid.org/0000-0003-3281-7683)
- Swati Malik (ORCID: https://orcid.org/0000-0002-3125-4332)
- Sagarika Biswas (ORCID: https://orcid.org/0000-0002-2017-1670)
- Debolina Chakraborty (ORCID: https://orcid.org/0009-0002-7515-770X)
- Ashish Sarkar (ORCID: https://orcid.org/0000-0002-0658-5463)
- Lovely Joshi
Institutions
- University of Delhi (IN)
- Institute of Genomics and Integrative Biology (IN)
- All India Institute of Medical Sciences (IN)
- Council of Scientific and Industrial Research (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s13075-024-03429-z
- Citations
- 10
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 4.70
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Council of Scientific and Industrial Research, India
- All-India Institute of Medical Sciences
- Academy of Scientific and Innovative Research
- Science and Engineering Research Board