The potential impact of inflammation on the lipid paradox in patients with acute myocardial infarction: a multicenter study
AMI patients with lower LDL-C levels had a higher risk of mortality. However, this association was only observed in those with high inflammatory risk. In contrast, the relationship between LDL-C and mortality risk was linear in patients with low inflammatory risk. This suggests the importance of considering inflammation when managing LDL-C levels in AMI patients.
Authors
- Guyu Zeng
- Lin Jiang (ORCID: https://orcid.org/0000-0003-1204-1865)
- Qingsheng Wang (ORCID: https://orcid.org/0000-0002-6411-984X)
- Xiaofang Tang (ORCID: https://orcid.org/0000-0002-9964-1953)
- Xiaogang Guo (ORCID: https://orcid.org/0000-0001-6754-1432)
- Yingqing Feng (ORCID: https://orcid.org/0000-0003-0443-5506)
- Yi Yao
- Xiaozeng Wang (ORCID: https://orcid.org/0000-0003-1979-0287)
- Ce Zhang (ORCID: https://orcid.org/0000-0003-0574-8141)
- Zhifang Wang (ORCID: https://orcid.org/0000-0002-9109-4422)
- Yaling Han
- Pei Zhu (ORCID: https://orcid.org/0000-0001-7411-0454)
- Jingjing Xu (ORCID: https://orcid.org/0000-0003-0390-4120)
- Yan Chen (ORCID: https://orcid.org/0000-0002-9376-037X)
- Ru Liu (ORCID: https://orcid.org/0000-0002-6132-7694)
- Yongzhen Zhang (ORCID: https://orcid.org/0000-0003-0571-8401)
- Ying Song
- Zheng Zhang
- Jinqing Yuan (ORCID: https://orcid.org/0000-0003-0284-1236)
- Zhenyu Liu (ORCID: https://orcid.org/0000-0001-5077-5777)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking Union Medical College Hospital (CN)
- General Hospital of Shenyang Military Region (CN)
- Peking University Third Hospital (CN)
- Xinxiang Central Hospital (CN)
- Guangdong Provincial People's Hospital (CN)
- Fu Wai Hospital (CN)
- First Hospital of Lanzhou University (CN)
- First Hospital of Qinhuangdao (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1186/s12916-024-03823-z
- Citations
- 17
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 9.74
Funders
- National Key Research and Development Program of China