Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study
Upadacitinib resulted in high rates of clinical remission at 8 and 16 weeks in this large real-world cohort of ulcerative colitis patients. Upadacitinib is effective in patients with prior tofacitinib exposure. Intestinal ultrasound shows significant rates of transmural remission at week 8, sustained through week 16.
Authors
- Robert Venning Bryant (ORCID: https://orcid.org/0000-0003-4229-3289)
- Daniel Lightowler (ORCID: https://orcid.org/0009-0005-8424-5594)
- Rupert W. Leong (ORCID: https://orcid.org/0000-0001-5944-3488)
- Imogen Hartley (ORCID: https://orcid.org/0009-0002-7325-1313)
- Britt Christensen (ORCID: https://orcid.org/0000-0002-8746-4275)
- Abhey Singh
- Robert Gilmore (ORCID: https://orcid.org/0000-0002-6648-658X)
- Abhinav Vasudevan (ORCID: https://orcid.org/0000-0001-5026-9014)
- Steven Kim (ORCID: https://orcid.org/0000-0002-1845-8410)
- Jakob Begun (ORCID: https://orcid.org/0000-0001-5256-7672)
- Mahy M. Mona
- Bridgette Andrew (ORCID: https://orcid.org/0000-0002-2657-4307)
- Nik S. Ding (ORCID: https://orcid.org/0000-0002-6232-1948)
- Yoon‐Kyo An (ORCID: https://orcid.org/0000-0002-1458-8015)
- Richard Fernandes (ORCID: https://orcid.org/0000-0002-9123-0228)
- Gregory Moore (ORCID: https://orcid.org/0000-0002-3689-8858)
- Jonathan Segal (ORCID: https://orcid.org/0000-0002-9668-0316)
- Jack West (ORCID: https://orcid.org/0000-0003-2732-8826)
- Tessa Greeve (ORCID: https://orcid.org/0000-0002-3061-8798)
- Aditya Mithanthaya (ORCID: https://orcid.org/0009-0003-0143-1654)
- Sangwoo Han
- Crispin Corte
- Kannan Venugopaul
- Arteen Arzivian
Institutions
- The University of Sydney (AU)
- The Royal Melbourne Hospital (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- The University of Western Australia (AU)
- Royal Prince Alfred Hospital (AU)
- Royal Perth Hospital (AU)
- Townsville Hospital (AU)
- Fiona Stanley Hospital (AU)
- Wexford General Hospital (IE)
- St Vincent's Hospital Melbourne (AU)
- Mater Research (AU)
- Eastern Health (AU)
- Queen Elizabeth Hospital (AU)
- Monash Health (AU)
- Mater Adult Hospital (AU)
- Monash University (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Intestinal Research
- Published
- 2024-12-22
- DOI
- https://doi.org/10.5217/ir.2024.00127
- Citations
- 11
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 6.05