Improvement of the method for the diagnosis of insulin resistance in horses

The diagnosis of equine metabolic syndrome has become an essential focus for many specialists, particularly in recent years. The primary risk factor for the development of metabolic syndrome is insulin dysfunction, which leads to both insulin resistance and hyperinsulinemia. This article addresses the pressing issue of diagnosing insulin resistance in horses. Modern diagnosis of equine metabolic syndrome is based on clinical examination, case history, and especially laboratory tests that evaluate various aspects of insulin resistance, along with other metabolic disorders, such as hyperglycemia. The main laboratory diagnostic methods include intravenous and oral dynamic glucose tolerance tests, which help assess insulin response to the introduction of carbohydrate components into the animal's body and the hormonal system's reaction to them [3]. The objective of the study was to explore the possibility of modifying the oral glucose tolerance test by using a domestically produced IG 42 invert syrup for diagnosing insulin resistance in horses. The article provides a detailed description of the research materials and methods, as well as the results of the test conducted on horses. It is noted that the use of the modified oral glucose tolerance test could be applied in practical veterinary medicine for diagnosing insulin resistance in horses. Based on the study results, it was established that the oral sugar test using IG 42 syrup could be employed in practical research to assess insulin resistance in horses by analyzing the dynamics of glucose and insulin concentrations. Future research will focus on evaluating the specificity and informativeness of this test in comparison with intravenous and combined glucose tolerance tests