Outcomes of Coronary Artery Bypass Grafting in Patients With Impaired Left Ventricular Function and the Role of Preoperative Myocardial Viability

Background Coronary artery bypass grafting (CABG) improves outcomes in patients with ischemic left ventricular (LV) dysfunction, but accurate patient selection remains critical. Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging aids in assessing myocardial viability, a key predictor of surgical outcomes. This study aimed to evaluate the impact of myocardial viability on postoperative outcomes in patients undergoing CABG. Methods This was a single-center prospective analysis of clinical outcomes in 37 patients with impaired LV function (mean ejection fraction: 35.59%); myocardial viability was assessed using LGE-CMR prior to CABG. Patient demographics, perioperative details, and short-term outcomes, including in-hospital mortality and recovery metrics, were analyzed. Results Patients exhibited high myocardial viability (mean: 88.16%), with an average of 2.35 non-viable segments. In-hospital mortality was 5.4% (n=2), and the mean hospital stay was six days. Patients with greater viability demonstrated better recovery and fewer complications. Multivessel coronary artery disease was prevalent (94.6%, n=35), with tailored graft configurations addressing individual anatomical and disease complexities. Conclusion LGE-CMR is a valuable tool for predicting outcomes in ischemic LV dysfunction. Myocardial viability strongly correlates with improved surgical recovery, highlighting the importance of integrating LGE-CMR into preoperative decision-making. Further studies are required to explore the long-term impact of myocardial viability on treatment outcomes and quality of life.

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Publication Details

Journal
Cureus
Published
2024-12-22
DOI
https://doi.org/10.7759/cureus.76198
Citations
2
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
0.81
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article

Outcomes of Coronary Artery Bypass Grafting in Patients With Impaired Left Ventricular Function and the Role of Preoperative Myocardial Viability

Raheel Khan, Ayesha Zahid, Muhammad Aasim, Nauman Shaukat et al.
2 citations
Cureus
Cardiac Imaging and Diagnostics
0.81
article

Outcomes of Coronary Artery Bypass Grafting in Patients With Impaired Left Ventricular Function and the Role of Preoperative Myocardial Viability

Raheel Khan, Ayesha Zahid, Muhammad Aasim, Nauman Shaukat, Raheela Aziz, Muhammad Awais, Jibran Ikram, Leonardo A Marquez Roa, Atta ul Mohsin
article en
2 citations

Abstract

Background Coronary artery bypass grafting (CABG) improves outcomes in patients with ischemic left ventricular (LV) dysfunction, but accurate patient selection remains critical. Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging aids in assessing myocardial viability, a key predictor of surgical outcomes. This study aimed to evaluate the impact of myocardial viability on postoperative outcomes in patients undergoing CABG. Methods This was a single-center prospective analysis of clinical outcomes in 37 patients with impaired LV function (mean ejection fraction: 35.59%); myocardial viability was assessed using LGE-CMR prior to CABG. Patient demographics, perioperative details, and short-term outcomes, including in-hospital mortality and recovery metrics, were analyzed. Results Patients exhibited high myocardial viability (mean: 88.16%), with an average of 2.35 non-viable segments. In-hospital mortality was 5.4% (n=2), and the mean hospital stay was six days. Patients with greater viability demonstrated better recovery and fewer complications. Multivessel coronary artery disease was prevalent (94.6%, n=35), with tailored graft configurations addressing individual anatomical and disease complexities. Conclusion LGE-CMR is a valuable tool for predicting outcomes in ischemic LV dysfunction. Myocardial viability strongly correlates with improved surgical recovery, highlighting the importance of integrating LGE-CMR into preoperative decision-making. Further studies are required to explore the long-term impact of myocardial viability on treatment outcomes and quality of life.

CureusVol. 16(12)
Cleveland Clinic (US), Outcomes Research Consortium (US), Royal Cornwall Hospital Trust (GB), Cleveland Foundation (US), Hayatabad Medical Complex (PK)
Openalex Percentile: Top 24%
Cardiac Imaging and Diagnostics
0.81
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