Comparison of molecular subtype composition between independent sets of primary and brain metastatic small cell lung carcinoma and matched samples
Our results indicate that the expression of subtype markers frequently changes during disease progression, and subtype analysis of the primary SCLC may not provide accurate information about the characteristics of the recurrent or metastatic tumour. Therefore, repeated sampling and subtyping may be necessary for subtype-specific targeted therapy.
Authors
- Dorottya Moldvai (ORCID: https://orcid.org/0009-0004-7831-6176)
- Bálint Scheich (ORCID: https://orcid.org/0000-0003-1354-646X)
- Ildikó Krencz (ORCID: https://orcid.org/0000-0003-3601-8723)
- Dániel Sztankovics (ORCID: https://orcid.org/0009-0007-3168-1151)
- Anna Sebestyén (ORCID: https://orcid.org/0000-0001-8814-4794)
- Titanilla Dankó (ORCID: https://orcid.org/0000-0002-7419-4560)
- Judit Pápay
- Fatime Szalai (ORCID: https://orcid.org/0009-0002-6129-6143)
Institutions
- Semmelweis University (HU)
Publication Details
- Journal
- Lung Cancer
- Published
- 2024-12-22
- DOI
- https://doi.org/10.1016/j.lungcan.2024.108071
- Citations
- 3
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Semmelweis Egyetem
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
- Nemzeti Kutatási, Fejlesztési és Innovaciós Alap
- National Research, Development and Innovation Office
- Division of Human Resource Development