Relationships between blood cadmium concentration and risk of nine cancers: evidence from the NHANES 1999–2018 and Mendelian randomization analyses
Elevated BCC was associated with an increased risk of bladder and lung cancers while demonstrating an inverse relationship with kidney and prostate cancers. MR analysis revealed that cadmium exposure may act as a protective factor against breast, cervical, colon, and kidney cancers, that must be confirmed with new studies.
Authors
- Ke Xu (ORCID: https://orcid.org/0000-0002-8130-1109)
- Guangyi Cheng (ORCID: https://orcid.org/0000-0001-9538-5027)
- Jiayi Chen (ORCID: https://orcid.org/0009-0003-8993-7579)
- Liantao Li (ORCID: https://orcid.org/0000-0002-8788-2880)
- Yuyan Wang (ORCID: https://orcid.org/0000-0003-3747-0762)
- Yu Shen (ORCID: https://orcid.org/0009-0005-3874-2514)
- Sijia Deng
- Shuguang Han
- Jiang Wang (ORCID: https://orcid.org/0009-0008-6154-4470)
- Bo Wang (ORCID: https://orcid.org/0009-0002-9278-190X)
Institutions
- Xuzhou Medical College (CN)
- Affiliated Hospital of Xuzhou Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-12-22
- DOI
- https://doi.org/10.1007/s12672-024-01692-9
- Citations
- 2
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.63
Funders
- China Postdoctoral Science Foundation