Neuroendocrine tumor discovered in a teenager following asthma misdiagnosis

Although relatively rare, neuroendocrine tumors (NETs) represent the most common type of endobronchial tumors in pediatric patients. Their clinical presentation lacks specificity, often leading to delayed diagnosis due to limited clinical suspicion. Mainly classified as low-grade malignant tumors (grade 1), they typically demonstrate favorable outcomes following surgical removal. However, local recurrence and/or metastases may occur in both low- and high-grade NET. We present the case of a 17-year-old girl initially misdiagnosed with asthma, later found to have a low-grade NET obstructing the left main bronchus. Surgical resection enabled complete tumor removal, and subsequent follow-up confirmed the postsurgical recovery. This case emphasizes the importance of familiarizing pediatricians and GP with the need for chest X-rays in all initial asthma diagnosis in order to eliminate differential diagnoses such as bronchial NET. This underscores the importance of a prompt diagnosis and follow-up care in similar cases.

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Publication Details

Journal
Archives de Pédiatrie
Published
2024-12-22
DOI
https://doi.org/10.1016/j.arcped.2024.11.002
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
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article

Neuroendocrine tumor discovered in a teenager following asthma misdiagnosis

Harriet Corvol, François Chalard, Nadia Nathan, Erik Hervieux et al.
Archives de Pédiatrie
Neuroendocrine Tumor Research Advances
article

Neuroendocrine tumor discovered in a teenager following asthma misdiagnosis

Harriet Corvol, François Chalard, Nadia Nathan, Erik Hervieux, Sophie Denamur, Elora Peulier‐Maitre, Aurore Coulomb
article en

Abstract

Although relatively rare, neuroendocrine tumors (NETs) represent the most common type of endobronchial tumors in pediatric patients. Their clinical presentation lacks specificity, often leading to delayed diagnosis due to limited clinical suspicion. Mainly classified as low-grade malignant tumors (grade 1), they typically demonstrate favorable outcomes following surgical removal. However, local recurrence and/or metastases may occur in both low- and high-grade NET. We present the case of a 17-year-old girl initially misdiagnosed with asthma, later found to have a low-grade NET obstructing the left main bronchus. Surgical resection enabled complete tumor removal, and subsequent follow-up confirmed the postsurgical recovery. This case emphasizes the importance of familiarizing pediatricians and GP with the need for chest X-rays in all initial asthma diagnosis in order to eliminate differential diagnoses such as bronchial NET. This underscores the importance of a prompt diagnosis and follow-up care in similar cases.

Archives de PédiatrieVol. 32(1)
Délégation Paris 5 (FR), Inserm (FR), Sorbonne Université (FR), Hôpital Armand-Trousseau (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre de Recherche Saint-Antoine (FR), Maladies génétiques d’expression pédiatrique
Good health and well-being
Openalex Percentile: Top 65%
Neuroendocrine Tumor Research Advances
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Neuroendocrine tumor discovered in a teenager following asthma misdiagnosis — Harriet Corvol, François Chalard, et al. · Archives de Pédiatrie (2024) | TGRS Research Map | TGRS