Circulating tumor DNA detection improves relapse prediction in epithelial ovarian cancer
Post-surgery MRD is superior to CA125 in predicting relapse in EOC. Patients exhibiting transient ctDNA clearance, as evaluated by post-ACT MRD, may require longitudinal monitoring. Baseline ctDNA detection could help determine whether post-surgery ctDNA monitoring should be performed.
Authors
- Ling Yang (ORCID: https://orcid.org/0000-0003-0193-0982)
- Pansong Li (ORCID: https://orcid.org/0000-0002-6278-5179)
- Jianting Guo (ORCID: https://orcid.org/0000-0002-5691-5707)
- Shan Zhu (ORCID: https://orcid.org/0000-0002-8710-7913)
- Sicong Xu (ORCID: https://orcid.org/0009-0000-0063-4589)
- Wei Gao (ORCID: https://orcid.org/0000-0003-3541-9568)
- Rutie Yin (ORCID: https://orcid.org/0000-0002-9221-6727)
- Yuhua Gong (ORCID: https://orcid.org/0000-0001-7893-2084)
- Jing Wang (ORCID: https://orcid.org/0000-0001-9981-5530)
- Xiao Xiao (ORCID: https://orcid.org/0000-0002-4328-0634)
- Mei Yu (ORCID: https://orcid.org/0000-0002-6070-2456)
- Yang Xiang (ORCID: https://orcid.org/0000-0002-9112-1021)
- Dongyan Cao (ORCID: https://orcid.org/0000-0002-7260-2495)
- Xuefeng Xia (ORCID: https://orcid.org/0000-0002-6390-1709)
- Xin Yi (ORCID: https://orcid.org/0000-0002-5884-0657)
- Yanfang Guan (ORCID: https://orcid.org/0000-0002-6722-2615)
- Peng Peng (ORCID: https://orcid.org/0009-0008-0963-7194)
- Jing Bai (ORCID: https://orcid.org/0000-0002-3323-2946)
- Yongjun Wang (ORCID: https://orcid.org/0000-0002-9112-816X)
- Ying Zhang (ORCID: https://orcid.org/0000-0001-5476-1524)
Institutions
- Central South University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Sichuan University (CN)
- Peking Union Medical College Hospital (CN)
- National Institute of Biological Sciences, Beijing (CN)
- West China Second University Hospital of Sichuan University (CN)
- Hunan Cancer Hospital (CN)
- Peking University International Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-22
- DOI
- https://doi.org/10.1186/s12885-024-13222-5
- Citations
- 7
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.00
Funders
- Peking Union Medical College Hospital