Incidental finding of diffuse Tc-99m methylene diphosphonate uptake in lungs in a patient with renal insufficiency and lymphoma

ABSTRACT Metastatic calcification of the lungs is presented with increased Tc-99m methylene diphosphonate (MDP) accumulation which was reported previously in usually benign causes including pneumonia and renal insufficiency. F-18 Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is the gold standard imaging modality in staging of the lymphoma and an accurate modality in showing dissemination of the disease. This case report presents a patient with primary unknown tumor presented by lythic bone metastasis in F-18 FDG PET/CT and increased Tc-99m MDP accumulation in both lungs due to the renal insufficiency in bone scintigraphy who was diagnosed as lymphoma by lymph node biopsy results.