Molecular Assay Versus Serology for Diagnosis of Scrub Typhus Among Patients With Acute Febrile Illness: A Retrospective Study

The study participants had symptoms like fever, cough, lymphadenopathy, rash, pain in the abdomen, and eschar. Our findings suggest that ELISA and DNA RT-PCR could be used for scrub typhus diagnosis among patients with febrile illness for > 5 and ≤ 5 days, respectively. Both diagnostic methods were found to possess a positive correlation. The findings of ELISA and DNA RT-PCR must be probed further.

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Publication Details

Journal
Cureus
Published
2024-12-20
DOI
https://doi.org/10.7759/cureus.76104
Primary Topic
Vector-borne infectious diseases
Type
article
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article

Molecular Assay Versus Serology for Diagnosis of Scrub Typhus Among Patients With Acute Febrile Illness: A Retrospective Study

Basanti Kumari Pathi, Kumudini Panigrahi, Dipti Pattnaik, Adrita Das et al.
1 links
Cureus
Vector-borne infectious diseases
article

Molecular Assay Versus Serology for Diagnosis of Scrub Typhus Among Patients With Acute Febrile Illness: A Retrospective Study

Basanti Kumari Pathi, Kumudini Panigrahi, Dipti Pattnaik, Adrita Das, Jyoti Prakash Sahoo
article en

Abstract

The study participants had symptoms like fever, cough, lymphadenopathy, rash, pain in the abdomen, and eschar. Our findings suggest that ELISA and DNA RT-PCR could be used for scrub typhus diagnosis among patients with febrile illness for > 5 and ≤ 5 days, respectively. Both diagnostic methods were found to possess a positive correlation. The findings of ELISA and DNA RT-PCR must be probed further.

CureusVol. 16(12)
All India Institute of Medical Sciences Bhubaneswar (IN)
Good health and well-being
Openalex Percentile: Top 77%
Vector-borne infectious diseases
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