Myocardial mRNA expression of interleukin-6 and hypoxia inducible factor-1α in neonates with congenital cardiac defects
Our study shows that besides inflammatory pathways, hypoxemia related pathways are activated in the myocardium of neonates with CHD. Myocardial expression of both IL-6-mRNA and HIF-1α-mRNA relates to biological markers of a worse po outcome.
Authors
- Nesrine Farhat (ORCID: https://orcid.org/0000-0002-5770-7870)
- Ruth Heying (ORCID: https://orcid.org/0000-0003-0743-0823)
- Jaime F. Vázquez-Jiménez
- Marie-Christine Seghaye
Institutions
- Universitätsklinikum Aachen (DE)
- Centre Hospitalier Universitaire de Liège (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Molecular and Cellular Pediatrics
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1186/s40348-024-00187-5
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29