Impact On Evidence-Based Clinical Practice of Considering Therapeutic Interventions in Patients with Chronic Kidney Disease

Background: Chronic kidney disease (CKD) is a progressive condition that may negatively affect musculoskeletal health. Patients with chronic kidney disease may experience better health outcomes when they engage in physical exercise. Objective: This literature study aims to provide a better understanding about the pathophysiology of chronic kidney disease and role of therapeutic intervention and its implication in patients with CKD and to evaluate the best treatment strategies for chronic kidney disease. Method: Relevant keywords will be used for the research through the electronic database PubMed, Medline, and Google scholar from January 2016 till January 2023. An open-source reference management software Zotero was used to manage bibliographic data and related research materials. Result: Databases such as PubMed, Medline, Google scholar in which 10 articles where initially screened and meet the inclusion criteria. In PUBMED, GOOGLE SCHOLAR, MEDLINE 56,214 citations were screened from January 2015 to January 2023. After applied inclusion/ exclusion criteria such as an abstract screen, full text screen, and during data extraction 56,204 articles were excluded. Conclusion: This review highlights the wide range of approaches used in clinical practice to evaluate physical performance and activity. Enhancing symptom management is critically needed to improve quality of life in advanced chronic kidney disease (CKD), even if minimizing mortality is still an important objective for kidney disease. KEYWORDS: chronic kidney disease, prevalence of CKD, Physiotherapy treatment strategies.