Implication of the enteric glia in the IBS-like colonic inflammation associated with endometriosis
We conclude that endometriosis can alter GI homeostasis by inducing colon inflammation, reactive gliosis, and ileal mast cell infiltration. Taken together this suggests endometriosis can mimic IBS histopathology beyond the symptomatology, reinforcing this disease's complexity and the need to treat it beyond the gynecological setting.
Authors
- Myrella L. Cruz
- Caroline B. Appleyard (ORCID: https://orcid.org/0000-0002-1211-4246)
- Ulises Rodriguez‐Cintron
- James P. Torres-Pirela
- Luis A. Rivera (ORCID: https://orcid.org/0000-0003-0724-9995)
Institutions
- Ponce Health Sciences University (PR)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1186/s12905-024-03480-7
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- American Physiological Society
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute on Minority Health and Health Disparities
- National Center for Complementary and Integrative Health