Oral Lichen Planus Associated With Autoimmune Hepatitis: A Rare Finding

ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated inflammatory condition affecting the oral mucosa. Autoimmune hepatitis (AIH) is a noncontagious rare chronic inflammatory disease of the liver characterised by interface hepatitis, circulating autoantibodies and increased serum IgG in the absence of other liver diseases. Only two cases of OLP in the background of AIH had been reported. Case Presentation A 24‐year‐old female presented to oral medicine clinic with an intraoral white lesion associated with pain while taking spicy and hot food. The pain was described as pricking‐like pain and limited to the tongue and bilateral buccal mucosa. She was diagnosed with AIH when she was 2 years old and is on Azathioprine 150 mg and oral prednisolone 5 mg once daily. She has no known allergy and risk habits. The social and dental history was noncontributory. Intraoral examination revealed poor oral hygiene, multiple unscrapable, nontender and nonfirm white lesions in the oral cavity. On biopsy, these lesions were confirmed as OLP. Conclusion We present a rare case of OLP in a known case of AIH, and this is the third to be reported in the literature. Future investigation might warrant a new insight on the correlations between AIH and OLP as there are increasing reports on OLP and autoimmune diseases.

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Publication Details

Journal
Oral Surgery
Published
2024-12-20
DOI
https://doi.org/10.1111/ors.12949
Primary Topic
Oral Health Pathology and Treatment
Type
article
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article

Oral Lichen Planus Associated With Autoimmune Hepatitis: A Rare Finding

Erica Pey Wen Hii, Anand Ramanathan, Saman Warnakulasuriya, Nadia Najwa bt Shuhairi et al.
Oral Surgery
Oral Health Pathology and Treatment
article

Oral Lichen Planus Associated With Autoimmune Hepatitis: A Rare Finding

Erica Pey Wen Hii, Anand Ramanathan, Saman Warnakulasuriya, Nadia Najwa bt Shuhairi, Toh Yen Fa, Valliammai Valiappan
article en

Abstract

ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated inflammatory condition affecting the oral mucosa. Autoimmune hepatitis (AIH) is a noncontagious rare chronic inflammatory disease of the liver characterised by interface hepatitis, circulating autoantibodies and increased serum IgG in the absence of other liver diseases. Only two cases of OLP in the background of AIH had been reported. Case Presentation A 24‐year‐old female presented to oral medicine clinic with an intraoral white lesion associated with pain while taking spicy and hot food. The pain was described as pricking‐like pain and limited to the tongue and bilateral buccal mucosa. She was diagnosed with AIH when she was 2 years old and is on Azathioprine 150 mg and oral prednisolone 5 mg once daily. She has no known allergy and risk habits. The social and dental history was noncontributory. Intraoral examination revealed poor oral hygiene, multiple unscrapable, nontender and nonfirm white lesions in the oral cavity. On biopsy, these lesions were confirmed as OLP. Conclusion We present a rare case of OLP in a known case of AIH, and this is the third to be reported in the literature. Future investigation might warrant a new insight on the correlations between AIH and OLP as there are increasing reports on OLP and autoimmune diseases.

Oral SurgeryVol. 18(2)
King's College London (GB), University of Malaya (MY), Mahsa University (MY)
No poverty
Openalex Percentile: Top 72%
Oral Health Pathology and Treatment
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Oral Lichen Planus Associated With Autoimmune Hepatitis: A Rare Finding — Erica Pey Wen Hii, Anand Ramanathan, et al. · Oral Surgery (2024) | TGRS Research Map | TGRS