Early Initiation Of Therapeutic Plasma Exchange In Yellow Phosphorus Poisoning: A Life-Saving Strategy – A Clinical Case Report

Rodenticides containing yellow phosphorus are one of the most common poisonings, which has high mortality seen among the southern Indian population. It is a very potent toxin, which when consumed results in acute liver failure followed by death. Presently there is no antidote available, and liver transplant is considered the only definitive treatment, while therapeutic plasma exchange (TPE) is regarded as a bridge therapy for liver transplantation. As per the Tamil Nadu Chapter of the Indian Society of Gastroenterology Guidelines (TN-ISG) for rodenticide poisoning, TPE is considered a non-transplant treatment option. Here we present a case of a 28 year old female with a yellow phosphorus poisoning case that was managed with early TPE. The patient responded well and was discharged after 8 days of hospitalization.