Contact heat evoked potentials reveal distinct patterns of spinal cord impairment in degenerative cervical myelopathy beyond <scp>MRI</scp> lesions
CHEPs revealed distinct patterns of spinal cord impairment independent of structural T2-positive lesions, which were associated with measures of cord motion. CHEPs thus provide valuable complementary diagnostic insights into spinal cord integrity beyond MRI. This is especially important in incipient myelopathy to inform early diagnosis and timely interventions before the development of definite cord lesions.
Authors
- Florian Wanivenhaus (ORCID: https://orcid.org/0000-0002-1735-4951)
- Markus Hupp (ORCID: https://orcid.org/0000-0003-0845-2514)
- Michèle Hubli (ORCID: https://orcid.org/0000-0001-6054-3283)
- Mazda Farshad (ORCID: https://orcid.org/0000-0002-7190-1127)
- Jan Rösner (ORCID: https://orcid.org/0000-0002-1973-1773)
- Patrick Freund (ORCID: https://orcid.org/0000-0002-4851-2246)
- Martin Schubert (ORCID: https://orcid.org/0000-0003-4495-6533)
- Maryam Seif (ORCID: https://orcid.org/0000-0002-9253-5680)
- Carl Moritz Zipser (ORCID: https://orcid.org/0000-0002-4396-4796)
- Armin Curt
- José Miguel Spirig (ORCID: https://orcid.org/0000-0001-5470-284X)
- Nikolai Pfender (ORCID: https://orcid.org/0000-0003-3933-7463)
- Paulina S. Scheuren (ORCID: https://orcid.org/0000-0001-7568-0133)
- Michael Betz (ORCID: https://orcid.org/0000-0002-0214-4003)
Institutions
- University of Bern (CH)
- University of British Columbia (CA)
- University of Zurich (CH)
- Aarhus University (DK)
- University Hospital of Bern (CH)
- Universitätsklinik Balgrist (CH)
- International Collaboration On Repair Discoveries (CA)
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Danish Pain Research Center (DK)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1111/ene.70001
- Citations
- 5
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Science Foundation
- Wings for Life
- Balgrist Stiftung
- Michael Smith Health Research BC
- International Foundation for Research in Paraplegia
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Lundbeckfonden
- Universität Zürich
- H. Lundbeck A/S