The Relation of Sex Difference with COVID-19 Outcomes: A Cross-sectional Study

Background: A virus known as SARS-CoV-2 is the cause of coronavirus disease 2019 (COVID-19). A novel coronavirus is causing the epidemic, which has given rise to millions of infections and deaths globally. SARS-CoV-2 infections can range in clinical presentation from asymptomatic to severe or critical. The disease is revealing profound differences between males and females in disease outcomes worldwide. Sex has been identified as additional risk factor that cause a varied COVID-19 outcomes. Objective: The present cross-sectional study aimed to make a comparison between males and females COVID-19 patients which was focused on demographic, clinical and biomarkers of the two group. Methodology: One hundred COVID-19 patients (48 males and 52 females) were participated in the study. Every patient underwent thorough laboratory evaluation, and the physicians diagnosed each one based on their complete medical history. Results: The findings showed that all of the biomarkers studied were elevated in both males and females, and some of these parameters showed a significant difference between males and females, others did not. Additionally, a significant correlation was found between the parameters that were analyzed within the same sex. Conclusion: According to the study's findings, both males and females are at risk and have higher levels of clinical and biochemical indicators; however, males are marginally more likely than females to get COVID-19, exhibit more severe symptoms, and have a poorer prognosis.