In silico and antibacterial studies of Thiadiazole and Triazole linked 1,8-Napthyridine derivatives

A series of thiadiazole and triazole linked 1,8-napthyridine derivatives were screened for antibacterial activity and docking studies were performed. Compared to the tetracycline, all these compounds have shown good to moderate antibacterial activity against Staphylococcus aureus, Bacillus cereus, Micrococcus luteus, Klebsiella pneumonia, Salmonella paratyphi A and Escherichia coli.

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Publication Details

Journal
Research Journal of Chemistry and Environment
Published
2024-11-30
DOI
https://doi.org/10.25303/291rjce046051
Primary Topic
Synthesis and biological activity
Type
article
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article

In silico and antibacterial studies of Thiadiazole and Triazole linked 1,8-Napthyridine derivatives

Pallooru Muni Bhaskar, Chittireddy Venkata Ramana Reddy, Laxminarayana Eppakayala, Lakshmi J. Bhargavi et al.
Research Journal of Chemistry and Environment
Synthesis and biological activity
article

In silico and antibacterial studies of Thiadiazole and Triazole linked 1,8-Napthyridine derivatives

Pallooru Muni Bhaskar, Chittireddy Venkata Ramana Reddy, Laxminarayana Eppakayala, Lakshmi J. Bhargavi, Donta Paramesh
article en

Abstract

A series of thiadiazole and triazole linked 1,8-napthyridine derivatives were screened for antibacterial activity and docking studies were performed. Compared to the tetracycline, all these compounds have shown good to moderate antibacterial activity against Staphylococcus aureus, Bacillus cereus, Micrococcus luteus, Klebsiella pneumonia, Salmonella paratyphi A and Escherichia coli.

Research Journal of Chemistry and EnvironmentVol. 29(1)
Openalex Percentile: Top 82%
Synthesis and biological activity
DOISourceOpenAlex
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In silico and antibacterial studies of Thiadiazole and Triazole linked 1,8-Napthyridine derivatives — Pallooru Muni Bhaskar, Chittireddy Venkata Ramana Reddy, et al. · Research Journal of Chemistry and Environment (2024) | TGRS Research Map | TGRS