An Unusual Case of Acute Abdomen With Jaundice

Adrenocortical carcinomas are rare but aggressive tumors that are frequently discovered as incidentalomas. Secretory tumors often lead to endocrine abnormalities, namely cushingoid features, virilization, or feminization. Non-functioning tumors, on the other hand, can be completely dormant with an insidious course or cause malaise, weight loss, abdominal pain, etc. Biochemical testing must be pursued in all patients with incidentalomas to detect pheochromocytoma, excess cortisol, or aldosterone secretion. In this report, we describe the case of a 37-year-old man who was lost to follow-up for two years following diagnosis with adrenal incidentaloma. This led to delayed diagnosis of adrenal carcinoma and eventual mortality. Periodic surveillance of adrenal incidentalomas is therefore imperative for timely interception of malignant lesions.

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Publication Details

Journal
Cureus
Published
2024-12-21
DOI
https://doi.org/10.7759/cureus.76155
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
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article

An Unusual Case of Acute Abdomen With Jaundice

John Bukasa-Kakamba, Aaron Ngandu, Daddy Liombo Mbiso, Nikita Wadhwani et al.
Cureus
Adrenal and Paraganglionic Tumors
article

An Unusual Case of Acute Abdomen With Jaundice

John Bukasa-Kakamba, Aaron Ngandu, Daddy Liombo Mbiso, Nikita Wadhwani, Shruti Wadhwani, Pascal Bayauli, Ayrton Bangolo, Simcha Weissman, Jean René M’buyamba-Kabangu, Aurelien Siasia, Ben Bepouka, Junior Koke Opanga, Jerry Nsimba Basolua, Serge Kakamba
article en

Abstract

Adrenocortical carcinomas are rare but aggressive tumors that are frequently discovered as incidentalomas. Secretory tumors often lead to endocrine abnormalities, namely cushingoid features, virilization, or feminization. Non-functioning tumors, on the other hand, can be completely dormant with an insidious course or cause malaise, weight loss, abdominal pain, etc. Biochemical testing must be pursued in all patients with incidentalomas to detect pheochromocytoma, excess cortisol, or aldosterone secretion. In this report, we describe the case of a 37-year-old man who was lost to follow-up for two years following diagnosis with adrenal incidentaloma. This led to delayed diagnosis of adrenal carcinoma and eventual mortality. Periodic surveillance of adrenal incidentalomas is therefore imperative for timely interception of malignant lesions.

CureusVol. 16(12)
Hackensack University Medical Center (US), University of Liège (BE), University of Kinshasa (CD), Centre Hospitalier Universitaire Ibn Rochd (MA), Hackensack Meridian Health (US)
Zero hunger
Openalex Percentile: Top 56%
Adrenal and Paraganglionic Tumors
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An Unusual Case of Acute Abdomen With Jaundice — John Bukasa-Kakamba, Aaron Ngandu, et al. · Cureus (2024) | TGRS Research Map | TGRS