EMC2 suppresses ferroptosis via regulating TFRC in nasopharyngeal carcinoma
EMC2 suppresses ferroptosis and promotes tumor progression, and the EMC2-TFRC axis is a novel ferroptosis regulatory pathway. EMC2 is a potentially biomarker and therapeutic target for NPC.
Authors
- Xianghui Chen (ORCID: https://orcid.org/0000-0002-0914-4452)
- Yongxian Wang (ORCID: https://orcid.org/0000-0002-6752-0436)
- Yuxia Zou (ORCID: https://orcid.org/0000-0002-0278-1117)
- Yi Huang (ORCID: https://orcid.org/0000-0003-0456-3428)
- Tingting Duan (ORCID: https://orcid.org/0000-0002-8173-7738)
- Zijie Zhou (ORCID: https://orcid.org/0000-0002-4620-1620)
- Qing Ye (ORCID: https://orcid.org/0000-0003-3797-8988)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0002-8763-289X)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1016/j.tranon.2024.102251
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Natural Science Foundation of Fujian Province
- Fujian Provincial Health Technology Project