Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression

In patients with ES-SCLC who received first-line PD-L1 inhibitors, continuing IBP extended second-line survival without increasing adverse events (AEs). A more pronounced OS benefit with IBP was noted within specific patient subgroups.

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Publication Details

Journal
Translational Oncology
Published
2024-12-21
DOI
https://doi.org/10.1016/j.tranon.2024.102249
Citations
4
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
1.13

Funders

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article

Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression

Jianfeng Peng, Ran Gao, Xiangjiao Meng, Xiaomei Liu et al.
4 citations
Translational Oncology
Lung Cancer Research Studies
1.13
article

Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression

Jianfeng Peng, Ran Gao, Xiangjiao Meng, Xiaomei Liu, Yimeng Wang, Zhaoqin Huang, X. Zhai, Peizhu Wu
article en
4 citations

Abstract

In patients with ES-SCLC who received first-line PD-L1 inhibitors, continuing IBP extended second-line survival without increasing adverse events (AEs). A more pronounced OS benefit with IBP was noted within specific patient subgroups.

Translational OncologyVol. 52
Shandong First Medical University (CN), Jinzhou Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Shandong Province, Key Technology Research and Development Program of Shandong
Good health and well-being
Openalex Percentile: Top 17%
Lung Cancer Research Studies
1.13
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