Progressive brain atrophy and cortical reorganization related to surgery in temporal lobe epilepsy
Progressive cortical atrophy existed in nonoperative TLE patients. Cortical remodeling indicated by postoperative GMV increase may arise mostly from the surgery itself, rather than postsurgical seizure outcomes. More significant GMV decrease in ipsilateral inferior frontal gyrus, putamen, and insula may imply their closer connections with resected regions in seizure-free patients.
Authors
- Dongmei An (ORCID: https://orcid.org/0000-0003-4622-0837)
- Xiuli Li (ORCID: https://orcid.org/0000-0003-3377-892X)
- Dong Chi Zhou (ORCID: https://orcid.org/0000-0001-7101-4125)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Yingjie Qin (ORCID: https://orcid.org/0000-0002-6020-5900)
- Wei Li (ORCID: https://orcid.org/0000-0001-7654-3069)
- Heng Zhang (ORCID: https://orcid.org/0000-0001-8866-0932)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Zero to Three (US)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1002/acn3.52285
- Citations
- 2
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province
- Sichuan University
- Natural Science Foundation of Sichuan Province
- West China Hospital, Sichuan University