APOL1 Genotype and HIV Infection: 20-Year Outcomes for CKD, Cardiovascular Disease, and Hypertension
Among treated persons with HIV, <i>APOL1</i> risk alleles were associated with CKD and eGFR decline, including an effect of 1 <i>APOL1</i> risk allele which took longer to manifest and was greater in individuals who did not achieve sustained viral suppression. Conversely, no association between <i>APOL1</i> risk alleles and incident hypertension or CVD was detected.
Authors
- Robert C. Kalayjian (ORCID: https://orcid.org/0000-0001-7114-726X)
- Edgar T. Overton (ORCID: https://orcid.org/0000-0002-4013-536X)
- Leslie A. Bruggeman (ORCID: https://orcid.org/0000-0001-5874-705X)
- Kunling Wu
- Zhenzhen Wu (ORCID: https://orcid.org/0000-0001-6751-6448)
- Christina M. Wyatt (ORCID: https://orcid.org/0000-0002-2900-8140)
- Katherine Tassiopoulos (ORCID: https://orcid.org/0000-0003-4773-2535)
- Frank J. Palella
Institutions
- Northwestern University (US)
- Cleveland Clinic (US)
- Harvard University (US)
- Duke University (US)
- University of Alabama at Birmingham (US)
- Cancer Research And Biostatistics (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1016/j.ekir.2024.12.022
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.68
Funders
- U.S. Department of Veterans Affairs
- National Institutes of Health