Excessive glutathione intake contributes to chemotherapy resistance in breast cancer: a propensity score matching analysis
Excessive GSH intake may contribute to chemotherapy resistance in breast cancer, and the levels of intracellular GSH and antioxidant enzymes are elevated in resistant patients after neoadjuvant chemotherapy, indicating that the standardization of GSH intake may assist in reducing chemotherapy resistance.
Authors
- Changzheng Zhu
- Shoukai Wang
- Wenkang Wang (ORCID: https://orcid.org/0000-0002-6325-1267)
- Wan-Yue Li (ORCID: https://orcid.org/0000-0002-9419-6256)
- Linjiao Jia
- Shuxin Kong
- Yuanxiang Lu (ORCID: https://orcid.org/0009-0004-2948-4931)
- Shuai Wang (ORCID: https://orcid.org/0000-0003-3946-4497)
- Wenwen Li (ORCID: https://orcid.org/0000-0001-9806-5045)
- Zhiyuan Zhang (ORCID: https://orcid.org/0009-0005-3691-8037)
- Wentao Li (ORCID: https://orcid.org/0000-0003-4856-1002)
- Jian Gao (ORCID: https://orcid.org/0000-0001-7636-911X)
- Yuqing Su
- Maosen Zhai (ORCID: https://orcid.org/0000-0003-0524-1914)
Institutions
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Henan Cancer Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2024-12-21
- DOI
- https://doi.org/10.1186/s12957-024-03626-9
- Citations
- 8
- Primary Topic
- Glutathione Transferases and Polymorphisms
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Henan Provincial People's Hospital